July 2024 Archive: Elsevier Reopens Review of Hydroxychloroquine Study
Elsevier has reopened a review of a highly debated hydroxychloroquine study first published in The Lancet. That study influenced treatment choices and policy early in the COVID-19 pandemic, then fell under heavy criticism because of data and methods tied to Surgisphere. The renewed review from Elsevier aims to clear up what went wrong and how such research made a big impact so fast.
What happened
The original paper claimed harmful effects from hydroxychloroquine in hospitalized COVID-19 patients. After publication, researchers pointed out inconsistencies and asked for raw data. Surgisphere, the data provider, refused to fully share patient-level data citing confidentiality, and independent audits could not verify the dataset. This led to retractions and a lot of confusion in hospitals and governments.
Why this matters and what to do
Bad or unreliable research changes medical guidance quickly. During 2020 several health agencies paused or adjusted trials based on that Lancet paper. When a study affects public policy, transparency matters more than ever. Elsevier’s renewed review could expose gaps in peer review, data sharing, or editorial checks that let flawed work pass.
If you read medical research, ask simple questions: Who supplied the data? Was raw data available for independent checks? How big was the study and were patient groups similar? Look for clear methods and independent validation. Trust journals that require data access or third-party audits. Skepticism helps—especially when headlines promise dramatic treatment effects.
For patients and families this is practical: don’t make medication decisions based on one study or a news story. Talk with your doctor about benefits and risks and ask whether the evidence comes from randomized trials or observational reports. Randomized controlled trials give stronger answers because they reduce bias.
What changes could come from Elsevier’s review? Expect recommendations on editorial practices: stronger demands for data transparency, clearer disclosures from authors about who owns data, and possibly routine verification steps when datasets come from third parties. Publishers might require independent audits before accepting high-impact findings that could change practice.
This archive month shows how scientific mistakes can ripple through healthcare. It also shows progress: publishers are willing to revisit past decisions when problems surface. That’s how science corrects itself — slowly but deliberately. Stay curious, read critically, and lean on trusted clinicians when new research affects your health choices.
Here are concrete steps to follow when a headline about a medical study appears: check if the research is peer-reviewed and which journal published it; look for accompanying editorials or independent commentaries; verify if other studies show similar results; watch for corrections, expressions of concern, or retractions listed on the journal site; and follow guidance from major health agencies like WHO or CDC. For journalists and policymakers, demand data access plans before citing studies that could change care. For clinicians, weigh single-study findings against the total evidence and consider waiting for confirmatory trials. Finally, remember that retraction doesn’t always mean fraud; sometimes errors happen. What matters is transparent correction so patients and providers can make safer choices. Stay informed and skeptical.
Elsevier Resumes Review of Debated Hydroxychloroquine COVID-19 Research

Elsevier has reignited an examination of a controversial study on hydroxychloroquine's impact on COVID-19 patients, originally published in *The Lancet*. The research, which significantly influenced global health policies, faced intense criticism over methodology and data reliability provided by Surgisphere. This renewed investigation aims to clarify the study's integrity and its influence on public health decisions.
- July 30 2024
- Tony Newman
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