Meloxicam alternatives

Meloxicam works for many, but stomach upset, kidney worries, or other side effects mean it’s not right for everyone. If meloxicam’s causing trouble or you need a different option, here are clear, practical alternatives you can discuss with your doctor.

Common drug substitutes

Over-the-counter pain relievers: Ibuprofen and naproxen are widely used NSAIDs. They reduce pain and swelling quickly but can irritate the stomach and affect blood pressure and kidneys if used long-term. Acetaminophen (paracetamol) eases pain without the same stomach risk, but it won’t reduce inflammation and can harm the liver if you exceed recommended doses.

Prescription NSAIDs and COX-2 inhibitors: Drugs like diclofenac and celecoxib may be options if meloxicam isn’t suitable. Celecoxib (a COX-2 inhibitor) often causes less stomach irritation but can raise cardiovascular risk in some people. Diclofenac comes in oral and topical forms; the topical gel can target joint pain with fewer systemic effects.

Topical NSAIDs: These gels or creams (diclofenac is common) sit on the skin over a painful joint and can cut pain for arthritis in knees, hands, or elbows. Topicals usually have fewer stomach and kidney effects than pills.

Injections: For stubborn joint pain, a corticosteroid injection into the joint can give strong, short-term relief. Hyaluronic acid injections are another option for knee osteoarthritis. Both require a clinician to administer and are not long-term fixes.

Non-drug options and safety tips

Physical therapy and exercise: Tailored strengthening and mobility work often reduces pain more than extra pills. Losing even a small amount of weight off a painful joint can make a big difference.

Heat, cold, and devices: Regular ice or heat, braces, and TENS units help many people manage flares at home without more medication.

Supplements and lifestyle changes: Omega-3s, turmeric/curcumin, and glucosamine are used by many—evidence varies, but some people feel benefit. Talk to your doctor before starting supplements, especially if you take blood thinners or other meds.

Safety first: If you have heart disease, kidney problems, active stomach ulcers, or are on blood thinners, some NSAIDs are risky. Always check with your clinician before switching drugs. If pain is severe, worsening, or limits daily life, ask for an evaluation—there may be a treatable cause that needs a different approach.

If meloxicam isn’t the right fit, you have options. Compare benefits and risks, try topical or non-drug strategies first when possible, and get a plan that fits your health history and goals.